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Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model

BACKGROUND: Proinflammatory interleukin-33 (IL-33) binds to its receptor ST2L and is involved in inflammation and the malignant behavior of cancer cells. However, the role of IL-33-ST2L and the IL-33 decoy receptor sST2 in the tumor microenvironment of pancreatic cancer is unclear. Because we previo...

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Detalles Bibliográficos
Autores principales: Takenaga, Keizo, Akimoto, Miho, Koshikawa, Nobuko, Nagase, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185704/
https://www.ncbi.nlm.nih.gov/pubmed/32340025
http://dx.doi.org/10.1371/journal.pone.0232230

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