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Catching a DUB in the act: novel ubiquitin-based active site directed probes
Protein ubiquitylation is an important regulator of protein function, localization and half-life. It plays a key role in most cellular processes including immune signaling. Deregulation of this process is a major causative factor for many diseases. A major advancement in the identification and chara...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185813/ https://www.ncbi.nlm.nih.gov/pubmed/25461387 http://dx.doi.org/10.1016/j.cbpa.2014.10.005 |