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Dynamin 2 interacts with α-actinin 4 to drive tumor cell invasion
The large GTPase Dynamin 2 (Dyn2) is known to increase the invasiveness of pancreatic cancer tumor cells, but the mechanisms by which Dyn2 regulates changes in the actin cytoskeleton to drive cell migration are still unclear. Here we report that a direct interaction between Dyn2 and the actin-bundli...
Autores principales: | Burton, Kevin M., Cao, Hong, Chen, Jing, Qiang, Li, Krueger, Eugene W., Johnson, Katherine M., Bamlet, William R., Zhang, Lizhi, McNiven, Mark A., Razidlo, Gina L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185896/ https://www.ncbi.nlm.nih.gov/pubmed/31967944 http://dx.doi.org/10.1091/mbc.E19-07-0395 |
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