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Spindle pole bodies function as signal amplifiers in the Mitotic Exit Network
The Mitotic Exit Network (MEN), a budding yeast Ras-like signal transduction cascade, translates nuclear position into a signal to exit from mitosis. Here we describe how scaffolding the MEN onto spindle pole bodies (SPB—centrosome equivalent) allows the MEN to couple the final stages of mitosis to...
Autores principales: | Campbell, Ian W., Zhou, Xiaoxue, Amon, Angelika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185974/ https://www.ncbi.nlm.nih.gov/pubmed/32074005 http://dx.doi.org/10.1091/mbc.E19-10-0584 |
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