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A complex regulatory landscape involved in the development of mammalian external genitals

Developmental genes are often controlled by large regulatory landscapes matching topologically associating domains (TADs). In various contexts, the associated chromatin backbone is modified by specific enhancer–enhancer and enhancer–promoter interactions. We used a TAD flanking the mouse HoxD cluste...

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Detalles Bibliográficos
Autores principales: Amândio, Ana Rita, Lopez-Delisle, Lucille, Bolt, Christopher Chase, Mascrez, Bénédicte, Duboule, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185996/
https://www.ncbi.nlm.nih.gov/pubmed/32301703
http://dx.doi.org/10.7554/eLife.52962

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