Cargando…
A complex regulatory landscape involved in the development of mammalian external genitals
Developmental genes are often controlled by large regulatory landscapes matching topologically associating domains (TADs). In various contexts, the associated chromatin backbone is modified by specific enhancer–enhancer and enhancer–promoter interactions. We used a TAD flanking the mouse HoxD cluste...
Autores principales: | Amândio, Ana Rita, Lopez-Delisle, Lucille, Bolt, Christopher Chase, Mascrez, Bénédicte, Duboule, Denis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185996/ https://www.ncbi.nlm.nih.gov/pubmed/32301703 http://dx.doi.org/10.7554/eLife.52962 |
Ejemplares similares
-
Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations
por: Bolt, Christopher Chase, et al.
Publicado: (2021) -
Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster
por: Amândio, Ana Rita, et al.
Publicado: (2021) -
Context-dependent enhancer function revealed by targeted inter-TAD relocation
por: Bolt, Christopher Chase, et al.
Publicado: (2022) -
Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken
por: Hintermann, Aurélie, et al.
Publicado: (2022) -
The constrained architecture of mammalian Hox gene clusters
por: Darbellay, Fabrice, et al.
Publicado: (2019)