Steroid-induced Lactic Acidosis in Diffuse Large B-cell Lymphoma

A previously healthy 53-year-old male with primary membranous nephropathy (positive anti phospholipase A2 antibody) presented to our hospital with worsening cough, shortness of breath, hypotension, and malaise. During his hospital stay, he quickly progressed to overt respiratory failure requiring me...

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Detalles Bibliográficos
Autores principales: Griffin, Daniel, Myadam, Rahul, Patel, Parth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186090/
https://www.ncbi.nlm.nih.gov/pubmed/32351825
http://dx.doi.org/10.7759/cureus.7446
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author Griffin, Daniel
Myadam, Rahul
Patel, Parth
author_facet Griffin, Daniel
Myadam, Rahul
Patel, Parth
author_sort Griffin, Daniel
collection PubMed
description A previously healthy 53-year-old male with primary membranous nephropathy (positive anti phospholipase A2 antibody) presented to our hospital with worsening cough, shortness of breath, hypotension, and malaise. During his hospital stay, he quickly progressed to overt respiratory failure requiring mechanical ventilation. Upon further workup, he met clinical criteria for tumor lysis syndrome due to an unknown diffuse large B-cell lymphoma, who underwent rapid cytolysis after starting stress dose steroids.
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spelling pubmed-71860902020-04-29 Steroid-induced Lactic Acidosis in Diffuse Large B-cell Lymphoma Griffin, Daniel Myadam, Rahul Patel, Parth Cureus Internal Medicine A previously healthy 53-year-old male with primary membranous nephropathy (positive anti phospholipase A2 antibody) presented to our hospital with worsening cough, shortness of breath, hypotension, and malaise. During his hospital stay, he quickly progressed to overt respiratory failure requiring mechanical ventilation. Upon further workup, he met clinical criteria for tumor lysis syndrome due to an unknown diffuse large B-cell lymphoma, who underwent rapid cytolysis after starting stress dose steroids. Cureus 2020-03-28 /pmc/articles/PMC7186090/ /pubmed/32351825 http://dx.doi.org/10.7759/cureus.7446 Text en Copyright © 2020, Griffin et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Griffin, Daniel
Myadam, Rahul
Patel, Parth
Steroid-induced Lactic Acidosis in Diffuse Large B-cell Lymphoma
title Steroid-induced Lactic Acidosis in Diffuse Large B-cell Lymphoma
title_full Steroid-induced Lactic Acidosis in Diffuse Large B-cell Lymphoma
title_fullStr Steroid-induced Lactic Acidosis in Diffuse Large B-cell Lymphoma
title_full_unstemmed Steroid-induced Lactic Acidosis in Diffuse Large B-cell Lymphoma
title_short Steroid-induced Lactic Acidosis in Diffuse Large B-cell Lymphoma
title_sort steroid-induced lactic acidosis in diffuse large b-cell lymphoma
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186090/
https://www.ncbi.nlm.nih.gov/pubmed/32351825
http://dx.doi.org/10.7759/cureus.7446
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