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Status of Lactate Dehydrogenase, Neutrophil-lymphocyte Ratio, Mean Platelet Volume, and Platelet-lymphocyte Ratio in Bell’s Palsy
Objective: The inflammatory and vascular disorders have been proposed in the pathogenesis of Bell’s palsy (BP). Several studies investigated the role of inflammation and ischemia in BP using white blood cell (WBC) count and its subtypes. Here, we aimed to investigate lactate dehydrogenase (LDH), neu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186107/ https://www.ncbi.nlm.nih.gov/pubmed/32351812 http://dx.doi.org/10.7759/cureus.7432 |
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author | Baklacı, Deniz Guler, İsmail Kuzucu, İhsan Kum, Rauf Oğuzhan Özcan, Müge |
author_facet | Baklacı, Deniz Guler, İsmail Kuzucu, İhsan Kum, Rauf Oğuzhan Özcan, Müge |
author_sort | Baklacı, Deniz |
collection | PubMed |
description | Objective: The inflammatory and vascular disorders have been proposed in the pathogenesis of Bell’s palsy (BP). Several studies investigated the role of inflammation and ischemia in BP using white blood cell (WBC) count and its subtypes. Here, we aimed to investigate lactate dehydrogenase (LDH), neutrophil-lymphocyte ratio (NLR), mean platelet volume (MPV), and platelet-lymphocyte ratio (PLR) in BP. Methods: The study was conducted on 76 patients with BP and 60 healthy controls. The comparison of LDH, NLR, MPV, and PLR was made between groups. The relationships between LDH, NLR, MPV, and PLR were also investigated. Results: The mean LDH concentrations and NLR were significantly high in BP group than in control group (p < 0.01, p < 0.05, respectively). There was no significant difference between groups in MPV and PLR (p = 0.195, p = 0.263, respectively). Conclusion: Our results support the diagnostic value of high LDH concentrations in BP patients. Further studies are needed to investigate the relationship between LDH and the severity and prognosis of BP. |
format | Online Article Text |
id | pubmed-7186107 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-71861072020-04-29 Status of Lactate Dehydrogenase, Neutrophil-lymphocyte Ratio, Mean Platelet Volume, and Platelet-lymphocyte Ratio in Bell’s Palsy Baklacı, Deniz Guler, İsmail Kuzucu, İhsan Kum, Rauf Oğuzhan Özcan, Müge Cureus Otolaryngology Objective: The inflammatory and vascular disorders have been proposed in the pathogenesis of Bell’s palsy (BP). Several studies investigated the role of inflammation and ischemia in BP using white blood cell (WBC) count and its subtypes. Here, we aimed to investigate lactate dehydrogenase (LDH), neutrophil-lymphocyte ratio (NLR), mean platelet volume (MPV), and platelet-lymphocyte ratio (PLR) in BP. Methods: The study was conducted on 76 patients with BP and 60 healthy controls. The comparison of LDH, NLR, MPV, and PLR was made between groups. The relationships between LDH, NLR, MPV, and PLR were also investigated. Results: The mean LDH concentrations and NLR were significantly high in BP group than in control group (p < 0.01, p < 0.05, respectively). There was no significant difference between groups in MPV and PLR (p = 0.195, p = 0.263, respectively). Conclusion: Our results support the diagnostic value of high LDH concentrations in BP patients. Further studies are needed to investigate the relationship between LDH and the severity and prognosis of BP. Cureus 2020-03-27 /pmc/articles/PMC7186107/ /pubmed/32351812 http://dx.doi.org/10.7759/cureus.7432 Text en Copyright © 2020, Baklacı et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Otolaryngology Baklacı, Deniz Guler, İsmail Kuzucu, İhsan Kum, Rauf Oğuzhan Özcan, Müge Status of Lactate Dehydrogenase, Neutrophil-lymphocyte Ratio, Mean Platelet Volume, and Platelet-lymphocyte Ratio in Bell’s Palsy |
title | Status of Lactate Dehydrogenase, Neutrophil-lymphocyte Ratio, Mean Platelet Volume, and Platelet-lymphocyte Ratio in Bell’s Palsy |
title_full | Status of Lactate Dehydrogenase, Neutrophil-lymphocyte Ratio, Mean Platelet Volume, and Platelet-lymphocyte Ratio in Bell’s Palsy |
title_fullStr | Status of Lactate Dehydrogenase, Neutrophil-lymphocyte Ratio, Mean Platelet Volume, and Platelet-lymphocyte Ratio in Bell’s Palsy |
title_full_unstemmed | Status of Lactate Dehydrogenase, Neutrophil-lymphocyte Ratio, Mean Platelet Volume, and Platelet-lymphocyte Ratio in Bell’s Palsy |
title_short | Status of Lactate Dehydrogenase, Neutrophil-lymphocyte Ratio, Mean Platelet Volume, and Platelet-lymphocyte Ratio in Bell’s Palsy |
title_sort | status of lactate dehydrogenase, neutrophil-lymphocyte ratio, mean platelet volume, and platelet-lymphocyte ratio in bell’s palsy |
topic | Otolaryngology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186107/ https://www.ncbi.nlm.nih.gov/pubmed/32351812 http://dx.doi.org/10.7759/cureus.7432 |
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