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Drosophila VCP/p97 Mediates Dynein-Dependent Retrograde Mitochondrial Motility in Axons
Valosin-containing protein (VCP), also called p97, is an evolutionarily conserved and ubiquitously expressed ATPase with diverse cellular functions. Dominant mutations in VCP are found in a late-onset multisystem degenerative proteinopathy. The neurological manifestations of the disorder include fro...
Autores principales: | Gonzalez, Ashley E., Wang, Xinnan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186335/ https://www.ncbi.nlm.nih.gov/pubmed/32373611 http://dx.doi.org/10.3389/fcell.2020.00256 |
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