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Sleep Electroencephalographic Response to Respiratory Events in Patients With Moderate Sleep Apnea–Hypopnea Syndrome
Sleep apnea–hypopnea syndrome is a common breathing disorder that can lead to organic brain injury, prevent memory consolidation, and cause other adverse mental-related complications. Brain activity while sleeping during respiratory events is related to these dysfunctions. In this study, we analyzed...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186482/ https://www.ncbi.nlm.nih.gov/pubmed/32372906 http://dx.doi.org/10.3389/fnins.2020.00310 |
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author | Zhou, Guolin Pan, Yu Yang, Juan Zhang, Xiangmin Guo, Xinwen Luo, Yuxi |
author_facet | Zhou, Guolin Pan, Yu Yang, Juan Zhang, Xiangmin Guo, Xinwen Luo, Yuxi |
author_sort | Zhou, Guolin |
collection | PubMed |
description | Sleep apnea–hypopnea syndrome is a common breathing disorder that can lead to organic brain injury, prevent memory consolidation, and cause other adverse mental-related complications. Brain activity while sleeping during respiratory events is related to these dysfunctions. In this study, we analyzed variations in electroencephalography (EEG) signals before, during, and after such events. Absolute and relative powers, as well as symbolic transfer entropy (STE) of scalp EEG signals, were calculated to unveil the activity of brain regions and information interactions between them, respectively. During the respiratory events, only low-frequency power increased during rapid eye movement (REM) stage (δ-band absolute and relative power) and N1 (δ- and θ-band absolute power, δ-band relative power) sleep. But absolute power increased in low- and medium-frequency bands (δ, θ, α, and σ bands), and relative power increased mainly in the medium-frequency band (α and σ bands) during stage N2 sleep. After the respiratory events, absolute power increased in all frequency bands and sleep stages, but relative power increased in medium and high frequencies. Regarding information interactions, the β-band STE decreased during and after events. In the γ band, the intrahemispheric STE increased during events and decreased afterward. Moreover, the interhemisphere STE increased after events during REM and stage N1 sleep. The EEG changes throughout respiratory events are supporting evidence for previous EEG knowledge of the impact of sleep apnea on the brain. These findings may provide insights into the influence of the sleep apnea–hypopnea syndrome on cognitive function and neuropsychiatric defects. |
format | Online Article Text |
id | pubmed-7186482 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71864822020-05-05 Sleep Electroencephalographic Response to Respiratory Events in Patients With Moderate Sleep Apnea–Hypopnea Syndrome Zhou, Guolin Pan, Yu Yang, Juan Zhang, Xiangmin Guo, Xinwen Luo, Yuxi Front Neurosci Neuroscience Sleep apnea–hypopnea syndrome is a common breathing disorder that can lead to organic brain injury, prevent memory consolidation, and cause other adverse mental-related complications. Brain activity while sleeping during respiratory events is related to these dysfunctions. In this study, we analyzed variations in electroencephalography (EEG) signals before, during, and after such events. Absolute and relative powers, as well as symbolic transfer entropy (STE) of scalp EEG signals, were calculated to unveil the activity of brain regions and information interactions between them, respectively. During the respiratory events, only low-frequency power increased during rapid eye movement (REM) stage (δ-band absolute and relative power) and N1 (δ- and θ-band absolute power, δ-band relative power) sleep. But absolute power increased in low- and medium-frequency bands (δ, θ, α, and σ bands), and relative power increased mainly in the medium-frequency band (α and σ bands) during stage N2 sleep. After the respiratory events, absolute power increased in all frequency bands and sleep stages, but relative power increased in medium and high frequencies. Regarding information interactions, the β-band STE decreased during and after events. In the γ band, the intrahemispheric STE increased during events and decreased afterward. Moreover, the interhemisphere STE increased after events during REM and stage N1 sleep. The EEG changes throughout respiratory events are supporting evidence for previous EEG knowledge of the impact of sleep apnea on the brain. These findings may provide insights into the influence of the sleep apnea–hypopnea syndrome on cognitive function and neuropsychiatric defects. Frontiers Media S.A. 2020-04-21 /pmc/articles/PMC7186482/ /pubmed/32372906 http://dx.doi.org/10.3389/fnins.2020.00310 Text en Copyright © 2020 Zhou, Pan, Yang, Zhang, Guo and Luo. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Zhou, Guolin Pan, Yu Yang, Juan Zhang, Xiangmin Guo, Xinwen Luo, Yuxi Sleep Electroencephalographic Response to Respiratory Events in Patients With Moderate Sleep Apnea–Hypopnea Syndrome |
title | Sleep Electroencephalographic Response to Respiratory Events in Patients With Moderate Sleep Apnea–Hypopnea Syndrome |
title_full | Sleep Electroencephalographic Response to Respiratory Events in Patients With Moderate Sleep Apnea–Hypopnea Syndrome |
title_fullStr | Sleep Electroencephalographic Response to Respiratory Events in Patients With Moderate Sleep Apnea–Hypopnea Syndrome |
title_full_unstemmed | Sleep Electroencephalographic Response to Respiratory Events in Patients With Moderate Sleep Apnea–Hypopnea Syndrome |
title_short | Sleep Electroencephalographic Response to Respiratory Events in Patients With Moderate Sleep Apnea–Hypopnea Syndrome |
title_sort | sleep electroencephalographic response to respiratory events in patients with moderate sleep apnea–hypopnea syndrome |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186482/ https://www.ncbi.nlm.nih.gov/pubmed/32372906 http://dx.doi.org/10.3389/fnins.2020.00310 |
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