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Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors

Immunotherapies are used as adjuvant therapies for cancers. However, knowledge of how traditional cancer treatments affect immunotherapies is limited. Using mouse models, we demonstrate that tumor-draining lymph nodes (TdLNs) are critical for tumor antigen-specific T cell response. However, removing...

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Detalles Bibliográficos
Autores principales: Zhao, Xianda, Kassaye, Beminet, Wangmo, Dechen, Lou, Emil, Subramanian, Subbaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186531/
https://www.ncbi.nlm.nih.gov/pubmed/32344378
http://dx.doi.org/10.1016/j.isci.2020.101056

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