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Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors
Immunotherapies are used as adjuvant therapies for cancers. However, knowledge of how traditional cancer treatments affect immunotherapies is limited. Using mouse models, we demonstrate that tumor-draining lymph nodes (TdLNs) are critical for tumor antigen-specific T cell response. However, removing...
Autores principales: | Zhao, Xianda, Kassaye, Beminet, Wangmo, Dechen, Lou, Emil, Subramanian, Subbaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186531/ https://www.ncbi.nlm.nih.gov/pubmed/32344378 http://dx.doi.org/10.1016/j.isci.2020.101056 |
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