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Alcohol ingestion induces pancreatic islet dysfunction and apoptosis via mediation of FGF21 resistance

BACKGROUND: Disruption of β-cell insulin secretion and viability caused by excessive ethanol consumption increases type 2 diabetes mellitus (T2DM) pathogenesis risk. Fibroblast growth factor 21 (FGF21) plays a significant role in regulating lipid and glucose homeostasis. Recently, FGF21, best known...

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Detalles Bibliográficos
Autores principales:	Yang, Bao Chen, Wu, Shang Ying, Leung, Po Sing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186649/ https://www.ncbi.nlm.nih.gov/pubmed/32355754 http://dx.doi.org/10.21037/atm.2020.02.129

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