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Enhanced glutamine utilization mediated by SLC1A5 and GPT2 is an essential metabolic feature of colorectal signet ring cell carcinoma with therapeutic potential

BACKGROUND: Colorectal signet-ring cell carcinoma (SRCC) is characterized as a rare subset of colorectal cancer with extremely poor prognosis and it is known to have low or negative (18)F fluorodeoxyglucose ((18)F-FDG) uptake. To date, no in-depth study revealing the metabolic features of colorectal...

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Detalles Bibliográficos
Autores principales:	Wang, Renjie, Xiang, Wenqiang, Xu, Ye, Han, Lingyu, Li, Qingguo, Dai, Weixing, Cai, Guoxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186745/ https://www.ncbi.nlm.nih.gov/pubmed/32355746 http://dx.doi.org/10.21037/atm.2020.03.31

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