Calculated parenteral initial treatment of bacterial infections: Bone and joint infections

This is the 10(th) chapter of the guideline “Calculated initial parenteral treatment of bacterial infections in adults – update 2018” in the 2(nd) updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been translated to address an international audience. This chapter deals with bacterial Infections of bones, joints and prosthetic joints. One of the most pressing points is that after an initial empirical therapy a targeted antimicrobial which penetrates well to the point of infection and is tolerated well over the usually long duration of the therapy is chosen.