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Chemical‐Shift Perturbations Reflect Bile Acid Binding to Norovirus Coat Protein: Recognition Comes in Different Flavors
Bile acids have been reported as important cofactors promoting human and murine norovirus (NoV) infections in cell culture. The underlying mechanisms are not resolved. Through the use of chemical shift perturbation (CSP) NMR experiments, we identified a low‐affinity bile acid binding site of a human...
Autores principales: | Creutznacher, Robert, Schulze, Eric, Wallmann, Georg, Peters, Thomas, Stein, Matthias, Mallagaray, Alvaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186840/ https://www.ncbi.nlm.nih.gov/pubmed/31644826 http://dx.doi.org/10.1002/cbic.201900572 |
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