Cargando…
SMIFH2 inhibition of platelets demonstrates a critical role for formin proteins in platelet cytoskeletal dynamics
BACKGROUND: Reorganization of the actin cytoskeleton is required for proper functioning of platelets following activation in response to vascular damage. Formins are a family of proteins that regulate actin polymerization and cytoskeletal organization via a number of domains including the FH2 domain...
Autores principales: | Green, Hannah L. H., Zuidscherwoude, Malou, Alenazy, Fawaz, Smith, Christopher W., Bender, Markus, Thomas, Steven G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186844/ https://www.ncbi.nlm.nih.gov/pubmed/31930764 http://dx.doi.org/10.1111/jth.14735 |
Ejemplares similares
-
Formin proteins in megakaryocytes and platelets: regulation of actin and microtubule dynamics
por: Zuidscherwoude, Malou, et al.
Publicado: (2018) -
Novel assay demonstrates that coronary artery disease patients have heightened procoagulant platelet response
por: Pasalic, L., et al.
Publicado: (2018) -
The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function
por: Holbrook, L-M, et al.
Publicado: (2012) -
Mean platelet size related to glycoprotein-specific autoantibodies and platelet-associated IgG
por: JAVELA, K, et al.
Publicado: (2007) -
Activation mechanism dependent surface exposure of cellular factor XIII on activated platelets and platelet microparticles
por: Somodi, Laura, et al.
Publicado: (2022)