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SMIFH2 inhibition of platelets demonstrates a critical role for formin proteins in platelet cytoskeletal dynamics

BACKGROUND: Reorganization of the actin cytoskeleton is required for proper functioning of platelets following activation in response to vascular damage. Formins are a family of proteins that regulate actin polymerization and cytoskeletal organization via a number of domains including the FH2 domain...

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Detalles Bibliográficos
Autores principales:	Green, Hannah L. H., Zuidscherwoude, Malou, Alenazy, Fawaz, Smith, Christopher W., Bender, Markus, Thomas, Steven G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	PLATELETS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186844/ https://www.ncbi.nlm.nih.gov/pubmed/31930764 http://dx.doi.org/10.1111/jth.14735

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