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Predicting educational achievement from genomic measures and socioeconomic status

The two best predictors of children's educational achievement available from birth are parents’ socioeconomic status (SES) and, recently, children's inherited DNA differences that can be aggregated in genome‐wide polygenic scores (GPS). Here, we chart for the first time the developmental i...

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Autores principales: von Stumm, Sophie, Smith‐Woolley, Emily, Ayorech, Ziada, McMillan, Andrew, Rimfeld, Kaili, Dale, Philip S., Plomin, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187229/
https://www.ncbi.nlm.nih.gov/pubmed/31758750
http://dx.doi.org/10.1111/desc.12925
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author von Stumm, Sophie
Smith‐Woolley, Emily
Ayorech, Ziada
McMillan, Andrew
Rimfeld, Kaili
Dale, Philip S.
Plomin, Robert
author_facet von Stumm, Sophie
Smith‐Woolley, Emily
Ayorech, Ziada
McMillan, Andrew
Rimfeld, Kaili
Dale, Philip S.
Plomin, Robert
author_sort von Stumm, Sophie
collection PubMed
description The two best predictors of children's educational achievement available from birth are parents’ socioeconomic status (SES) and, recently, children's inherited DNA differences that can be aggregated in genome‐wide polygenic scores (GPS). Here, we chart for the first time the developmental interplay between these two predictors of educational achievement at ages 7, 11, 14 and 16 in a sample of almost 5,000 UK school children. We show that the prediction of educational achievement from both GPS and SES increases steadily throughout the school years. Using latent growth curve models, we find that GPS and SES not only predict educational achievement in the first grade but they also account for systematic changes in achievement across the school years. At the end of compulsory education at age 16, GPS and SES, respectively, predict 14% and 23% of the variance of educational achievement. Analyses of the extremes of GPS and SES highlight their influence and interplay: In children who have high GPS and come from high SES families, 77% go to university, whereas 21% of children with low GPS and from low SES backgrounds attend university. We find that the associations of GPS and SES with educational achievement are primarily additive, suggesting that their joint influence is particularly dramatic for children at the extreme ends of the distribution.
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spelling pubmed-71872292020-04-28 Predicting educational achievement from genomic measures and socioeconomic status von Stumm, Sophie Smith‐Woolley, Emily Ayorech, Ziada McMillan, Andrew Rimfeld, Kaili Dale, Philip S. Plomin, Robert Dev Sci Papers The two best predictors of children's educational achievement available from birth are parents’ socioeconomic status (SES) and, recently, children's inherited DNA differences that can be aggregated in genome‐wide polygenic scores (GPS). Here, we chart for the first time the developmental interplay between these two predictors of educational achievement at ages 7, 11, 14 and 16 in a sample of almost 5,000 UK school children. We show that the prediction of educational achievement from both GPS and SES increases steadily throughout the school years. Using latent growth curve models, we find that GPS and SES not only predict educational achievement in the first grade but they also account for systematic changes in achievement across the school years. At the end of compulsory education at age 16, GPS and SES, respectively, predict 14% and 23% of the variance of educational achievement. Analyses of the extremes of GPS and SES highlight their influence and interplay: In children who have high GPS and come from high SES families, 77% go to university, whereas 21% of children with low GPS and from low SES backgrounds attend university. We find that the associations of GPS and SES with educational achievement are primarily additive, suggesting that their joint influence is particularly dramatic for children at the extreme ends of the distribution. John Wiley and Sons Inc. 2019-12-18 2020-05 /pmc/articles/PMC7187229/ /pubmed/31758750 http://dx.doi.org/10.1111/desc.12925 Text en © 2019 The Authors. Developmental Science published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Papers
von Stumm, Sophie
Smith‐Woolley, Emily
Ayorech, Ziada
McMillan, Andrew
Rimfeld, Kaili
Dale, Philip S.
Plomin, Robert
Predicting educational achievement from genomic measures and socioeconomic status
title Predicting educational achievement from genomic measures and socioeconomic status
title_full Predicting educational achievement from genomic measures and socioeconomic status
title_fullStr Predicting educational achievement from genomic measures and socioeconomic status
title_full_unstemmed Predicting educational achievement from genomic measures and socioeconomic status
title_short Predicting educational achievement from genomic measures and socioeconomic status
title_sort predicting educational achievement from genomic measures and socioeconomic status
topic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187229/
https://www.ncbi.nlm.nih.gov/pubmed/31758750
http://dx.doi.org/10.1111/desc.12925
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