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The prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: A systematic review and meta‐analysis

OBJECTIVE: To investigate the effect of non‐small cell lung cancer (NSCLC) combined with Chronic Obstructive Pulmonary Disease (COPD) on prognosis, so as to provide help to clinical diagnosis and treatment. METHODS: PubMed, Web of Science and the Medline were used to retrieve studies reported from 1...

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Autores principales: Wu, Ke, Wang, Jing, Zhao, Limin, Wang, Pei, Duan, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187245/
https://www.ncbi.nlm.nih.gov/pubmed/31905419
http://dx.doi.org/10.1111/crj.13144
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author Wu, Ke
Wang, Jing
Zhao, Limin
Wang, Pei
Duan, Qi
author_facet Wu, Ke
Wang, Jing
Zhao, Limin
Wang, Pei
Duan, Qi
author_sort Wu, Ke
collection PubMed
description OBJECTIVE: To investigate the effect of non‐small cell lung cancer (NSCLC) combined with Chronic Obstructive Pulmonary Disease (COPD) on prognosis, so as to provide help to clinical diagnosis and treatment. METHODS: PubMed, Web of Science and the Medline were used to retrieve studies reported from 1950 to 2019. If the study reported the prognosis of COPD with NSCLC, the study was included and the relevant information was extracted and the data analyzed. The standard mean deviation (SMD) of 95% confidence interval was used in this meta‐analysis. RESULTS: A total of 851 data studies were reviewed for eligibility, eventually, 12 case‐control studies were included in this systematic review and meta‐analysis. The sample sizes for company's studies of NSCLC ranged from 85 to 10 378, with a total number of 14 164, including 2450 COPD and 9395 Non‐COPD. Meta‐analyses showed that concomitant COPD was associated with poorer OS compared with patients without COPD (Fixed: HR: 1.16; 95% CI: 1.08‐1.25. Random: HR: 1.07; CI: 0.92‐1.24), with a significant heterogeneity across studies (I (2) = 45%, P = 0.04). CONCLUSION: Our study showed that patients with combined COPD had an impact on the prognosis and survival rate of SCLC patients.
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spelling pubmed-71872452020-04-28 The prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: A systematic review and meta‐analysis Wu, Ke Wang, Jing Zhao, Limin Wang, Pei Duan, Qi Clin Respir J Original Articles OBJECTIVE: To investigate the effect of non‐small cell lung cancer (NSCLC) combined with Chronic Obstructive Pulmonary Disease (COPD) on prognosis, so as to provide help to clinical diagnosis and treatment. METHODS: PubMed, Web of Science and the Medline were used to retrieve studies reported from 1950 to 2019. If the study reported the prognosis of COPD with NSCLC, the study was included and the relevant information was extracted and the data analyzed. The standard mean deviation (SMD) of 95% confidence interval was used in this meta‐analysis. RESULTS: A total of 851 data studies were reviewed for eligibility, eventually, 12 case‐control studies were included in this systematic review and meta‐analysis. The sample sizes for company's studies of NSCLC ranged from 85 to 10 378, with a total number of 14 164, including 2450 COPD and 9395 Non‐COPD. Meta‐analyses showed that concomitant COPD was associated with poorer OS compared with patients without COPD (Fixed: HR: 1.16; 95% CI: 1.08‐1.25. Random: HR: 1.07; CI: 0.92‐1.24), with a significant heterogeneity across studies (I (2) = 45%, P = 0.04). CONCLUSION: Our study showed that patients with combined COPD had an impact on the prognosis and survival rate of SCLC patients. John Wiley and Sons Inc. 2020-02-03 2020-04 /pmc/articles/PMC7187245/ /pubmed/31905419 http://dx.doi.org/10.1111/crj.13144 Text en © 2020 The Authors. The Clinical Respiratory Journal published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Wu, Ke
Wang, Jing
Zhao, Limin
Wang, Pei
Duan, Qi
The prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: A systematic review and meta‐analysis
title The prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: A systematic review and meta‐analysis
title_full The prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: A systematic review and meta‐analysis
title_fullStr The prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: A systematic review and meta‐analysis
title_full_unstemmed The prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: A systematic review and meta‐analysis
title_short The prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: A systematic review and meta‐analysis
title_sort prognosis of non‐small cell lung cancer combined with chronic obstructive pulmonary disease: a systematic review and meta‐analysis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187245/
https://www.ncbi.nlm.nih.gov/pubmed/31905419
http://dx.doi.org/10.1111/crj.13144
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