A Thorough QT Study to Evaluate the Effects of a Supratherapeutic Dose of Sertraline on Cardiac Repolarization in Healthy Subjects

The effect of steady‐state supratherapeutic sertraline (Zoloft) on QT interval was assessed in a single‐center, randomized, 3‐way crossover, double‐blind, placebo‐ and moxifloxacin‐controlled thorough QT study. Healthy adults received sertraline 400 mg/day, moxifloxacin 400 mg, and placebo, with a w...

Descripción completa

Detalles Bibliográficos
Autores principales: Abbas, Richat, Riley, Steve, LaBadie, Robert R., Bachinsky, Mary, Chappell, Phillip B., Crownover, Penelope H., Damle, Bharat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187253/
https://www.ncbi.nlm.nih.gov/pubmed/31777203
http://dx.doi.org/10.1002/cpdd.749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187253/
https://www.ncbi.nlm.nih.gov/pubmed/31777203
http://dx.doi.org/10.1002/cpdd.749

Ejemplares similares