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Brain imaging measurements of fibrillar amyloid‐β burden, paired helical filament tau burden, and atrophy in cognitively unimpaired persons with two, one, and no copies of the APOE ε4 allele

INTRODUCTION: We previously characterized associations between brain imaging measurements of amyloid‐β (Aβ) plaque burden and apolipoprotein E (APOE ) ε4 gene dose in a small number of cognitively unimpaired late‐middle‐aged APOE ε4 homozygotes (HMs), heterozygotes (HTs), and noncarriers (NCs). We n...

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Detalles Bibliográficos
Autores principales:	Ghisays, Valentina, Goradia, Dhruman D., Protas, Hillary, Bauer, Robert J., Devadas, Vivek, Tariot, Pierre N., Lowe, Val J., Knopman, David S., Petersen, Ronald C., Jack, Clifford R., Caselli, Richard J., Su, Yi, Chen, Kewei, Reiman, Eric M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Featured Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187298/ https://www.ncbi.nlm.nih.gov/pubmed/31831374 http://dx.doi.org/10.1016/j.jalz.2019.08.195

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