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Mid‐manufacturing storage: Antibody stability after chromatography and precipitation based capture steps
Antibodies of the IgG2 subclass were captured from the clarified cell culture fluid either by protein A chromatography or by polyethylene glycol precipitation. The captured intermediates were stored as neutralized eluates (protein A chromatography) or in solid form as polyethylene glycol precipitate...
Autores principales: | Krepper, Walpurga, Burgstaller, Daniel, Jungbauer, Alois, Satzer, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187330/ https://www.ncbi.nlm.nih.gov/pubmed/31622530 http://dx.doi.org/10.1002/btpr.2928 |
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