Cargando…

Efficient Screening for Ternary Molecular Ionic Cocrystals Using a Complementary Mechanosynthesis and Computational Structure Prediction Approach

The discovery of molecular ionic cocrystals (ICCs) of active pharmaceutical ingredients (APIs) widens the opportunities for optimizing the physicochemical properties of APIs whilst facilitating the delivery of multiple therapeutic agents. However, ICCs are often observed serendipitously in crystalli...

Descripción completa

Detalles Bibliográficos
Autores principales: Shunnar, Abeer F., Dhokale, Bhausaheb, Karothu, Durga Prasad, Bowskill, David H., Sugden, Isaac J., Hernandez, Hector H., Naumov, Panče, Mohamed, Sharmarke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187361/
https://www.ncbi.nlm.nih.gov/pubmed/31793669
http://dx.doi.org/10.1002/chem.201904672