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Population Pharmacokinetics of Glasdegib in Patients With Advanced Hematologic Malignancies and Solid Tumors

Glasdegib is an inhibitor of the Hedgehog pathway recently approved in the United States for the treatment of acute myeloid leukemia. A population pharmacokinetic analysis was conducted to characterize the kinetic behavior of glasdegib and its sources of variability (covariates) by utilizing data fr...

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Detalles Bibliográficos
Autores principales:	Lin, Swan, Shaik, Naveed, Martinelli, Giovanni, Wagner, Andrew J., Cortes, Jorge, Ruiz‐Garcia, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Pharmacometrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187372/ https://www.ncbi.nlm.nih.gov/pubmed/31769065 http://dx.doi.org/10.1002/jcph.1556

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