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Optimizing beta cell function through mesenchymal stromal cell‐mediated mitochondria transfer

Pretransplant islet culture is associated with the loss of islet cell mass and insulin secretory function. Insulin secretion from islet β‐cells is primarily controlled by mitochondrial ATP generation in response to elevations in extracellular glucose. Coculture of islets with mesenchymal stromal cel...

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Detalles Bibliográficos
Autores principales: Rackham, Chloe L., Hubber, Ella L., Czajka, Anna, Malik, Afshan N., King, Aileen J. F., Jones, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187381/
https://www.ncbi.nlm.nih.gov/pubmed/31912945
http://dx.doi.org/10.1002/stem.3134

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