Mesencephalic Astrocyte‐Derived Neurotrophic Factor Inhibits Liver Cancer Through Small Ubiquitin‐Related Modifier (SUMO)ylation‐Related Suppression of NF‐κB/Snail Signaling Pathway and Epithelial‐Mesenchymal Transition

BACKGROUND AND AIMS: Endoplasmic reticulum (ER) stress is associated with liver inflammation and hepatocellular carcinoma (HCC). However, how ER stress links inflammation and HCC remains obscure. Mesencephalic astrocyte‐derived neurotrophic factor (MANF) is an ER stress‐inducible secretion protein t...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Wu, Zhengsheng, Han, Dan, Wei, Chuansheng, Liang, Yanyan, Jiang, Tongcui, Chen, Lu, Sha, Manqi, Cao, Yajie, Huang, Fan, Geng, Xiaoping, Yu, Jishuang, Shen, Yujun, Wang, Hua, Feng, Lijie, Wang, Dong, Fang, Shengyun, Wang, Siying, Shen, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187412/
https://www.ncbi.nlm.nih.gov/pubmed/31469428
http://dx.doi.org/10.1002/hep.30917

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