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Self-reactive T cells induce and perpetuate chronic relapsing arthritis

BACKGROUND: CD4(+) T cells play a central role during the early stages of rheumatoid arthritis (RA), but to which extent they are required for the perpetuation of the disease is still not fully understood. The aim of the current study was to obtain conclusive evidence that T cells drive chronic rela...

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Detalles Bibliográficos
Autores principales: Tuncel, Jonatan, Holmberg, Jens, Haag, Sabrina, Hopkins, Malin Hultqvist, Wester-Rosenlöf, Lena, Carlsen, Stefan, Olofsson, Peter, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187533/
https://www.ncbi.nlm.nih.gov/pubmed/32345366
http://dx.doi.org/10.1186/s13075-020-2104-7