Genomic and Metabolomic Polymorphism among Experimentally Selected Paromomycin-Resistant Leishmania donovani Strains

Understanding the mechanism(s) underpinning drug resistance could lead to novel treatments to reverse the increased tolerance of a pathogen. In this study, paromomycin (PMM) resistance (PMM(r)) was induced in three Nepalese clinical strains of Leishmania donovani with different inherent susceptibili...

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Detalles Bibliográficos
Autores principales: Shaw, C. D., Imamura, H., Downing, T., Blackburn, G., Westrop, G. D., Cotton, J. A., Berriman, M., Sanders, M., Rijal, S., Coombs, G. H., Dujardin, J. C., Carter, K. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187574/
https://www.ncbi.nlm.nih.gov/pubmed/31658971
http://dx.doi.org/10.1128/AAC.00904-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187574/
https://www.ncbi.nlm.nih.gov/pubmed/31658971
http://dx.doi.org/10.1128/AAC.00904-19

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