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The Sle1 Cell Wall Amidase Is Essential for β-Lactam Resistance in Community-Acquired Methicillin-Resistant Staphylococcus aureus USA300

Most clinically relevant methicillin-resistant Staphylococcus aureus (MRSA) strains have become resistant to β-lactams antibiotics through horizontal acquisition of the mecA gene encoding PBP2a, a peptidoglycan transpeptidase with low affinity for β-lactams. The level of resistance conferred by mecA...

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Detalles Bibliográficos
Autores principales:	Thalsø-Madsen, Ida, Torrubia, Fernando Ruiz, Xu, Lijuan, Petersen, Andreas, Jensen, Camilla, Frees, Dorte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187620/ https://www.ncbi.nlm.nih.gov/pubmed/31685469 http://dx.doi.org/10.1128/AAC.01931-19

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