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False-negative testing for severe acute respiratory syndrome coronavirus 2: consideration in obstetrical care

Because the obstetrical population seems to have a high proportion of asymptomatic patients who are carriers of severe acute respiratory syndrome coronavirus 2, universal testing has been proposed as a strategy to risk-stratify all obstetrical admissions and guide infection prevention protocols. Her...

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Detalles Bibliográficos
Autores principales: Kelly, Jeannie C., Dombrowksi, Michael, O’Neil-Callahan, Micaela, Kernberg, Annessa S., Frolova, Antonina I., Stout, Molly J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187860/
https://www.ncbi.nlm.nih.gov/pubmed/32346672
http://dx.doi.org/10.1016/j.ajogmf.2020.100130
Descripción
Sumario:Because the obstetrical population seems to have a high proportion of asymptomatic patients who are carriers of severe acute respiratory syndrome coronavirus 2, universal testing has been proposed as a strategy to risk-stratify all obstetrical admissions and guide infection prevention protocols. Here, we describe a case of a critically ill obstetrical patient with all the clinical symptoms of coronavirus disease 2019 and 3 false-negative results of nasopharyngeal swabs for molecular testing. We review and discuss the uncertain clinical characteristics of current severe acute respiratory syndrome coronavirus 2 molecular testing and the implications of false-negative results in the obstetrical population.