Multi-focal Lytic Lesions in a Patient with Myelofibrosis: A Case Report

Myelofibrosis is a rare disorder that is classified as one of the myeloproliferative disorders. This particular disorder results in the abnormal proliferation of hematopoietic stem cells in the bone marrow. In some cases, such as ours, pathologic fractures can occur due to skeletal manifestations. W...

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Detalles Bibliográficos
Autores principales: Burnham, Robert R, Johnson, Bailey, Lomasney, Laurie M, Borys, Dariusz, Cooper, Anna R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188018/
https://www.ncbi.nlm.nih.gov/pubmed/32351853
http://dx.doi.org/10.7759/cureus.7475
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author Burnham, Robert R
Johnson, Bailey
Lomasney, Laurie M
Borys, Dariusz
Cooper, Anna R
author_facet Burnham, Robert R
Johnson, Bailey
Lomasney, Laurie M
Borys, Dariusz
Cooper, Anna R
author_sort Burnham, Robert R
collection PubMed
description Myelofibrosis is a rare disorder that is classified as one of the myeloproliferative disorders. This particular disorder results in the abnormal proliferation of hematopoietic stem cells in the bone marrow. In some cases, such as ours, pathologic fractures can occur due to skeletal manifestations. We report on a rare finding of rapidly progressive lytic lesions in multiple regions throughout the body. This presentation of myelofibrosis behaving in a metastatic-like fashion has not been previously described.
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spelling pubmed-71880182020-04-29 Multi-focal Lytic Lesions in a Patient with Myelofibrosis: A Case Report Burnham, Robert R Johnson, Bailey Lomasney, Laurie M Borys, Dariusz Cooper, Anna R Cureus Pathology Myelofibrosis is a rare disorder that is classified as one of the myeloproliferative disorders. This particular disorder results in the abnormal proliferation of hematopoietic stem cells in the bone marrow. In some cases, such as ours, pathologic fractures can occur due to skeletal manifestations. We report on a rare finding of rapidly progressive lytic lesions in multiple regions throughout the body. This presentation of myelofibrosis behaving in a metastatic-like fashion has not been previously described. Cureus 2020-03-30 /pmc/articles/PMC7188018/ /pubmed/32351853 http://dx.doi.org/10.7759/cureus.7475 Text en Copyright © 2020, Burnham et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Burnham, Robert R
Johnson, Bailey
Lomasney, Laurie M
Borys, Dariusz
Cooper, Anna R
Multi-focal Lytic Lesions in a Patient with Myelofibrosis: A Case Report
title Multi-focal Lytic Lesions in a Patient with Myelofibrosis: A Case Report
title_full Multi-focal Lytic Lesions in a Patient with Myelofibrosis: A Case Report
title_fullStr Multi-focal Lytic Lesions in a Patient with Myelofibrosis: A Case Report
title_full_unstemmed Multi-focal Lytic Lesions in a Patient with Myelofibrosis: A Case Report
title_short Multi-focal Lytic Lesions in a Patient with Myelofibrosis: A Case Report
title_sort multi-focal lytic lesions in a patient with myelofibrosis: a case report
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188018/
https://www.ncbi.nlm.nih.gov/pubmed/32351853
http://dx.doi.org/10.7759/cureus.7475
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