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Preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis

We developed a preoperative assessment system to predict surgical workload in hand-assisted laparoscopic donor nephrectomy (HALDNx) using the normal-based linear discriminant rule (NLDR). A total of 128 cases of left HALDNx performed by a single operator were used as training data. Surgical workload...

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Autores principales: Iwadoh, Kazuhiro, Nakajima, Ichiro, Koyama, Ichiro, Nitta, Kosaku, Fuchinoue, Shohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188199/
https://www.ncbi.nlm.nih.gov/pubmed/32343697
http://dx.doi.org/10.1371/journal.pone.0227546
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author Iwadoh, Kazuhiro
Nakajima, Ichiro
Koyama, Ichiro
Nitta, Kosaku
Fuchinoue, Shohei
author_facet Iwadoh, Kazuhiro
Nakajima, Ichiro
Koyama, Ichiro
Nitta, Kosaku
Fuchinoue, Shohei
author_sort Iwadoh, Kazuhiro
collection PubMed
description We developed a preoperative assessment system to predict surgical workload in hand-assisted laparoscopic donor nephrectomy (HALDNx) using the normal-based linear discriminant rule (NLDR). A total of 128 cases of left HALDNx performed by a single operator were used as training data. Surgical workload was measured by operative time. The optimized model had 9 explanatory variables: age, total protein, total cholesterol, number of renal arteries (numberRA), 4 variables of perinephric fat (PNF), and thickness of subcutaneous fat. This model was validated using cross-validation and the .632 estimator to estimate discrimination rates with future test data. PNF and numberRA were the predominant factors affecting workload followed by the computed tomography value of PNF, body weight, and male sex. The estimated accuracy of the prediction system was 94.6%. The complication rate was 9.38% and did not correlate with surgical workload. We also made our program available online for constructing assessment functions from other cohort data. In conclusion, the surgical workload of HALDNx could be predicted with PNF and numberRA as the dominant risk factors.
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spelling pubmed-71881992020-05-06 Preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis Iwadoh, Kazuhiro Nakajima, Ichiro Koyama, Ichiro Nitta, Kosaku Fuchinoue, Shohei PLoS One Research Article We developed a preoperative assessment system to predict surgical workload in hand-assisted laparoscopic donor nephrectomy (HALDNx) using the normal-based linear discriminant rule (NLDR). A total of 128 cases of left HALDNx performed by a single operator were used as training data. Surgical workload was measured by operative time. The optimized model had 9 explanatory variables: age, total protein, total cholesterol, number of renal arteries (numberRA), 4 variables of perinephric fat (PNF), and thickness of subcutaneous fat. This model was validated using cross-validation and the .632 estimator to estimate discrimination rates with future test data. PNF and numberRA were the predominant factors affecting workload followed by the computed tomography value of PNF, body weight, and male sex. The estimated accuracy of the prediction system was 94.6%. The complication rate was 9.38% and did not correlate with surgical workload. We also made our program available online for constructing assessment functions from other cohort data. In conclusion, the surgical workload of HALDNx could be predicted with PNF and numberRA as the dominant risk factors. Public Library of Science 2020-04-28 /pmc/articles/PMC7188199/ /pubmed/32343697 http://dx.doi.org/10.1371/journal.pone.0227546 Text en © 2020 Iwadoh et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Iwadoh, Kazuhiro
Nakajima, Ichiro
Koyama, Ichiro
Nitta, Kosaku
Fuchinoue, Shohei
Preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis
title Preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis
title_full Preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis
title_fullStr Preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis
title_full_unstemmed Preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis
title_short Preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis
title_sort preoperative assessment system for hand-assisted laparoscopic donor nephrectomy by discriminant analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188199/
https://www.ncbi.nlm.nih.gov/pubmed/32343697
http://dx.doi.org/10.1371/journal.pone.0227546
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