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Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organising protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers

Plasmodium falciparum causes the most lethal form of malaria. The cooperation of heat shock protein (Hsp) 70 and 90 is thought to facilitate folding of select group of cellular proteins that are crucial for cyto-protection and development of the parasites. Hsp70 and Hsp90 are brought into a function...

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Detalles Bibliográficos
Autores principales: Makumire, Stanley, Zininga, Tawanda, Vahokoski, Juha, Kursula, Inari, Shonhai, Addmore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188212/
https://www.ncbi.nlm.nih.gov/pubmed/32343703
http://dx.doi.org/10.1371/journal.pone.0226657