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Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organising protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers
Plasmodium falciparum causes the most lethal form of malaria. The cooperation of heat shock protein (Hsp) 70 and 90 is thought to facilitate folding of select group of cellular proteins that are crucial for cyto-protection and development of the parasites. Hsp70 and Hsp90 are brought into a function...
Autores principales: | Makumire, Stanley, Zininga, Tawanda, Vahokoski, Juha, Kursula, Inari, Shonhai, Addmore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188212/ https://www.ncbi.nlm.nih.gov/pubmed/32343703 http://dx.doi.org/10.1371/journal.pone.0226657 |
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