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Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT)

AIM: Metabolic reprograming is crucial in the proliferation of hepatocellular carcinoma (HCC). Canagliflozin (CANA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, affects various metabolisms. We investigated the effects of CANA on proliferation and metabolic reprograming of HCC cell lines usin...

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Detalles Bibliográficos
Autores principales:	Nakano, Dan, Kawaguchi, Takumi, Iwamoto, Hideki, Hayakawa, Masako, Koga, Hironori, Torimura, Takuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188283/ https://www.ncbi.nlm.nih.gov/pubmed/32343721 http://dx.doi.org/10.1371/journal.pone.0232283

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