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Differential expression of the T-cell inhibitor TIGIT in glioblastoma and MS

OBJECTIVE: To identify coinhibitory immune pathways important in the brain, we hypothesized that comparison of T cells in lesions from patients with MS with tumor-infiltrating T cells (TILs) from patients with glioblastoma multiforme may reveal novel targets for immunotherapy. METHODS: We collected...

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Detalles Bibliográficos
Autores principales: Lucca, Liliana E., Lerner, Benjamin A., Park, Calvin, DeBartolo, Danielle, Harnett, Brian, Kumar, Varun P., Ponath, Gerald, Raddassi, Khadir, Huttner, Anita, Hafler, David A., Pitt, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188477/
https://www.ncbi.nlm.nih.gov/pubmed/32269065
http://dx.doi.org/10.1212/NXI.0000000000000712