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Haemoglobin causes neuronal damage in vivo which is preventable by haptoglobin

After subarachnoid haemorrhage, prolonged exposure to toxic extracellular haemoglobin occurs in the brain. Here, we investigate the role of haemoglobin neurotoxicity in vivo and its prevention. In humans after subarachnoid haemorrhage, haemoglobin in cerebrospinal fluid was associated with neurofila...

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Detalles Bibliográficos
Autores principales: Garland, Patrick, Morton, Matthew J, Haskins, William, Zolnourian, Ardalan, Durnford, Andrew, Gaastra, Ben, Toombs, Jamie, Heslegrave, Amanda J, More, John, Okemefuna, Azubuike I, Teeling, Jessica L, Graversen, Jonas H, Zetterberg, Henrik, Moestrup, Soren K, Bulters, Diederik O, Galea, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188517/
https://www.ncbi.nlm.nih.gov/pubmed/32346673
http://dx.doi.org/10.1093/braincomms/fcz053

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