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miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer

BACKGROUND: Metabolic reprogramming towards aerobic glycolysis in cancer supports unrestricted cell proliferation, survival and chemoresistance. The molecular bases of these processes are still undefined. Recent reports suggest crucial roles for microRNAs. Here, we provide new evidence of the implic...

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Detalles Bibliográficos
Autores principales:	Barisciano, Giovannina, Colangelo, Tommaso, Rosato, Valeria, Muccillo, Livio, Taddei, Maria Letizia, Ippolito, Luigi, Chiarugi, Paola, Galgani, Mario, Bruzzaniti, Sara, Matarese, Giuseppe, Fassan, Matteo, Agostini, Marco, Bergamo, Francesca, Pucciarelli, Salvatore, Carbone, Annalucia, Mazzoccoli, Gianluigi, Colantuoni, Vittorio, Bianchi, Fabrizio, Sabatino, Lina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188668/ https://www.ncbi.nlm.nih.gov/pubmed/32132656 http://dx.doi.org/10.1038/s41416-020-0773-2

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