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New survival standards for advanced melanoma

The expectation for survival in patients with advanced melanoma now exceeds 50% at 5 years in patients treated with first-line combination ipilimumab and nivolumab, despite this regimen being associated with substantial toxicity. We discuss the latest updates from the Checkmate-067 study, framing th...

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Detalles Bibliográficos
Autores principales: Spain, Lavinia, Larkin, James, Turajlic, Samra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188675/
https://www.ncbi.nlm.nih.gov/pubmed/32063602
http://dx.doi.org/10.1038/s41416-020-0738-5
Descripción
Sumario:The expectation for survival in patients with advanced melanoma now exceeds 50% at 5 years in patients treated with first-line combination ipilimumab and nivolumab, despite this regimen being associated with substantial toxicity. We discuss the latest updates from the Checkmate-067 study, framing the role of this combination in practice today.