Non-inferiority randomised phase 3 trial comparing two radiation schedules (single vs. five fractions) in malignant spinal cord compression

BACKGROUND: The optimal EBRT schedule for MSCC is undetermined. Our aim was to determine whether a single fraction (SF) was non-inferior to five daily fractions (5Fx), for functional motor outcome. METHODS: Patients not proceeding with surgical decompression in this multicentre non-inferiority, Phas...

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Detalles Bibliográficos
Autores principales: Thirion, Pierre G., Dunne, Mary T., Kelly, Paul J., Flavin, Aileen, O’Sullivan, Joe M., Hacking, Dayle, Sasiadek, Wojciech, Small, Cormac, Pomeroy, Maeve M., Martin, Joseph, McArdle, Orla, Parker, Imelda, O’Sullivan, Lydia S., Shannon, Aoife M., Clayton-Lea, Angela, Collins, Conor D., Stevenson, Michael R., Alvarez-Iglesias, Alberto, Armstrong, John G., Moriarty, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188681/
https://www.ncbi.nlm.nih.gov/pubmed/32157242
http://dx.doi.org/10.1038/s41416-020-0768-z

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