Cytotoxic T Lymphocytes Regenerated from iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model

Current adoptive T cell therapies conducted in an autologous setting are costly, time consuming, and depend on the quality of the patient's T cells. To address these issues, we developed a strategy in which cytotoxic T lymphocytes (CTLs) are regenerated from iPSCs that were originally derived f...

Descripción completa

Detalles Bibliográficos
Autores principales: Kashima, Soki, Maeda, Takuya, Masuda, Kyoko, Nagano, Seiji, Inoue, Takamitsu, Takeda, Masashi, Kono, Yuka, Kobayashi, Takashi, Saito, Shigeyoshi, Higuchi, Takahiro, Ichise, Hiroshi, Kobayashi, Yuka, Iwaisako, Keiko, Terada, Koji, Agata, Yasutoshi, Numakura, Kazuyuki, Saito, Mitsuru, Narita, Shintaro, Yasukawa, Masaki, Ogawa, Osamu, Habuchi, Tomonori, Kawamoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188741/
https://www.ncbi.nlm.nih.gov/pubmed/32259478
http://dx.doi.org/10.1016/j.isci.2020.100998

Ejemplares similares

Ejemplares similares