Microencapsulated Insulin-Like Growth Factor-1 therapy improves cardiac function and reduces fibrosis in a porcine acute myocardial infarction model

Insulin-like growth factor-1 (IGF-1) has demonstrated beneficial effects after myocardial infarction (MI). Microencapsulation of IGF-1 could potentially improve results. We aimed to test the effect of an intracoronary (IC) infusion of microencapsulated IGF-1 in a swine acute MI model. For that purpo...

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Detalles Bibliográficos
Autores principales: Báez-Díaz, Claudia, Blanco-Blázquez, Virginia, Sánchez-Margallo, Francisco-Miguel, Bayes-Genis, Antoni, González, Irene, Abad, Ana, Steendam, Rob, Franssen, Okke, Palacios, Itziar, Sánchez, Belén, Gálvez-Montón, Carolina, Crisóstomo, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188803/
https://www.ncbi.nlm.nih.gov/pubmed/32346015
http://dx.doi.org/10.1038/s41598-020-64097-y

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