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Initiation Factor 3 is Dispensable For Mitochondrial Translation in Cultured Human Cells
The initiation of protein synthesis in bacteria is ruled by three canonical factors: IF1, IF2, and IF3. This system persists in human mitochondria; however, it functions in a rather different way due to specialization and adaptation to the organellar micro-environment. We focused on human mitochondr...
Autores principales: | Chicherin, Ivan V., Baleva, Maria V., Levitskii, Sergey A., Dashinimaev, Erdem B., Krasheninnikov, Igor A., Kamenski, Piotr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188818/ https://www.ncbi.nlm.nih.gov/pubmed/32346061 http://dx.doi.org/10.1038/s41598-020-64139-5 |
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