In vitro and in vivo efficacy of combinations of colistin and different endolysins against clinical strains of multi-drug resistant pathogens

The emergence of multidrug resistant (MDR) pathogenic bacteria is jeopardizing the value of antimicrobials, which had previously changed the course of medical science. In this study, we identified endolysins ElyA1 and ElyA2 (GH108-PG3 family), present in the genome of bacteriophages Ab1051Φ and Ab10...

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Detalles Bibliográficos
Autores principales: Blasco, Lucia, Ambroa, Anton, Trastoy, Rocio, Bleriot, Ines, Moscoso, Miriam, Fernández-Garcia, Laura, Perez-Nadales, Elena, Fernández-Cuenca, Felipe, Torre-Cisneros, Julian, Oteo-Iglesias, Jesus, Oliver, Antonio, Canton, Rafael, Kidd, Tim, Navarro, Ferran, Miró, Elisenda, Pascual, Alvaro, Bou, German, Martínez-Martínez, Luis, Tomas, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188820/
https://www.ncbi.nlm.nih.gov/pubmed/32346029
http://dx.doi.org/10.1038/s41598-020-64145-7

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