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Targeting CD133 reverses drug-resistance via the AKT/NF-κB/MDR1 pathway in colorectal cancer

BACKGROUND: Recent studies have shown that multidrug resistance may be induced by the high stemness of cancer cells. Following prolonged chemotherapy, MDR protein 1 (MDR1) and CD133 increase in CRC, but the relationship between them is unclear. METHODS: The relationship between MDR and CSC propertie...

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Detalles Bibliográficos
Autores principales:	Yuan, Zeting, Liang, Xin, Zhan, Yueping, Wang, Ziyuan, Xu, Jian, Qiu, Yanyan, Wang, Jie, Cao, Yijun, Le, Van-Minh, Ly, Hai-Trieu, Xu, Jianhua, Li, Wei, Yin, Peihao, Xu, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188877/ https://www.ncbi.nlm.nih.gov/pubmed/32203206 http://dx.doi.org/10.1038/s41416-020-0783-0

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