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The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice

Curcumin is a naturally occurring p300-histone acetyltransferase (p300-HAT) inhibitor that suppresses cardiomyocyte hypertrophy and the development of heart failure in experimental animal models. To enhance the therapeutic potential of curcumin against heart failure, we produced a series of syntheti...

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Detalles Bibliográficos
Autores principales:	Shimizu, Kana, Sunagawa, Yoichi, Funamoto, Masafumi, Wakabayashi, Hiroki, Genpei, Mai, Miyazaki, Yusuke, Katanasaka, Yasufumi, Sari, Nurmila, Shimizu, Satoshi, Katayama, Ayumi, Shibata, Hiroyuki, Iwabuchi, Yoshiharu, Kakeya, Hideaki, Wada, Hiromichi, Hasegawa, Koji, Morimoto, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188884/ https://www.ncbi.nlm.nih.gov/pubmed/32346115 http://dx.doi.org/10.1038/s41598-020-64207-w

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