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5-FU-Induced Upregulation of Exosomal PD-L1 Causes Immunosuppression in Advanced Gastric Cancer Patients

Although the cytotoxic chemotherapeutic agent 5-fluorouracil (5-FU) is generally considered to directly kill cancer cells and exert immunostimulatory effects in advanced gastric cancer, accumulating evidence indicates that it upregulates the expression of PD-L1, a representative immune checkpoint bl...

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Detalles Bibliográficos
Autores principales:	Zhang, Min, Fan, Yibo, Che, Xiaofang, Hou, Kezuo, Zhang, Chaoxu, Li, Ce, Wen, Ti, Wang, Shuo, Cheng, Yu, Liu, Yunpeng, Qu, Xiujuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188923/ https://www.ncbi.nlm.nih.gov/pubmed/32391259 http://dx.doi.org/10.3389/fonc.2020.00492

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