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Efficient synthesis of piperazinyl amides of 18β-glycyrrhetinic acid

In the present study, a practical method to prepare piperazinyl amides of 18β-glycyrrhetinic acid was developed. Two main procedures for the construction of important intermediate 8 are discussed. One procedure involves the amidation of 1-Boc-piperazine with 3-acetyl-18β-glycyrrhetinic acid, prepare...

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Detalles Bibliográficos
Autores principales: Cai, Dong, Zhang, ZhiHua, Meng, Yufan, Zhu, KaiLi, Chen, LiYi, Yu, ChangXiang, Yu, ChangWei, Fu, ZiYi, Yang, DianShen, Gong, YiXia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188925/
https://www.ncbi.nlm.nih.gov/pubmed/32395183
http://dx.doi.org/10.3762/bjoc.16.73