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NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein
Proteasomes are essential protease complexes that maintain cellular homeostasis, and aberrant proteasomal activity supports cancer development. The regulatory mechanisms and biological function of the ubiquitin-26S proteasome have been studied extensively, while those of the ubiquitin-independent 20...
Autores principales: | Waku, Tsuyoshi, Nakamura, Nanami, Koji, Misaki, Watanabe, Hidenori, Katoh, Hiroki, Tatsumi, Chika, Tamura, Natsuko, Hatanaka, Atsushi, Hirose, Shuuhei, Katayama, Hiroyuki, Tani, Misato, Kubo, Yuki, Hamazaki, Jun, Hamakubo, Takao, Watanabe, Akira, Murata, Shigeo, Kobayashi, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189095/ https://www.ncbi.nlm.nih.gov/pubmed/32123008 http://dx.doi.org/10.1128/MCB.00597-19 |
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