Bmi1 inhibitor PTC-209 promotes Chemically-induced Direct Cardiac Reprogramming of cardiac fibroblasts into cardiomyocytes

The development of therapeutic approaches based on direct cardiac reprogramming of fibroblasts into induced-cardiomyocytes (iCM) has emerged as an attractive strategy to repair the injured myocardium. The identification of the mechanisms driving lineage conversion represents a crucial step toward th...

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Detalles Bibliográficos
Autores principales: Testa, Gianluca, Russo, Michele, Di Benedetto, Giorgia, Barbato, Matteo, Parisi, Silvia, Pirozzi, Flora, Tocchetti, Carlo Gabriele, Abete, Pasquale, Bonaduce, Domenico, Russo, Tommaso, Passaro, Fabiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189257/
https://www.ncbi.nlm.nih.gov/pubmed/32346096
http://dx.doi.org/10.1038/s41598-020-63992-8

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