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The downregulated membrane expression of CD18 in CD34(+) cells defines a primitive population of human hematopoietic stem cells
BACKGROUND: CD18 is the common beta subunit of β(2) integrins, which are expressed on hematopoietic cells. β(2) integrins are essential for cell adhesion and leukocyte trafficking. METHODS: Here we have analyzed the expression of CD18 in different subsets of human hematopoietic stem and progenitor c...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189462/ https://www.ncbi.nlm.nih.gov/pubmed/32345365 http://dx.doi.org/10.1186/s13287-020-01672-0 |