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LSD1 inhibition yields functional insulin-producing cells from human embryonic stem cells
BACKGROUND: Human embryonic stem cells represent a potentially unlimited source of insulin-producing cells for diabetes therapy. While tremendous progress has been made in directed differentiation of human embryonic stem cells into IPCs in vitro, the mechanisms controlling its differentiation and fu...
Autores principales: | He, Fei, Li, Ning, Huang, Hai-Bo, Wang, Jing-Bo, Yang, Xiao-Fei, Wang, Hua-Dong, Huang, Wei, Li, Fu-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189473/ https://www.ncbi.nlm.nih.gov/pubmed/32345350 http://dx.doi.org/10.1186/s13287-020-01674-y |
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